JOAQUIM MANOEL DE MACEDO

\d͡ʒˈə͡ʊkwɪm mˈanə͡ʊl də masˈɪdə͡ʊ], \d‍ʒˈə‍ʊkwɪm mˈanə‍ʊl də masˈɪdə‍ʊ], \dʒ_ˈəʊ_k_w_ɪ_m m_ˈa_n_əʊ_l d_ə m_a_s_ˈɪ_d_əʊ]\

Definitions of JOAQUIM MANOEL DE MACEDO

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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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