RAFAEL MARIA BARALT

\ɹˌɑːfa͡ɪˈɛl mɐɹˈiːə bˈaɹɒlt], \ɹˌɑːfa‍ɪˈɛl mɐɹˈiːə bˈaɹɒlt], \ɹ_ˌɑː_f_aɪ_ˈɛ_l m_ɐ_ɹ_ˈiː__ə b_ˈa_ɹ_ɒ_l_t]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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