PROXIMAL RENAL TUBULAR DYSFUNCTION

\pɹˈɒksɪmə͡l ɹˈiːnə͡l tjˈuːbjʊlə dɪsfˈʌŋkʃən], \pɹˈɒksɪmə‍l ɹˈiːnə‍l tjˈuːbjʊlə dɪsfˈʌŋkʃən], \p_ɹ_ˈɒ_k_s_ɪ_m_əl ɹ_ˈiː_n_əl t_j_ˈuː_b_j_ʊ_l_ə d_ɪ_s_f_ˈʌ_ŋ_k_ʃ_ə_n]\

Definitions of PROXIMAL RENAL TUBULAR DYSFUNCTION

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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