SPIRILLUM TYROGENUM
\spɪɹˈɪləm tˈa͡ɪɹə͡ʊd͡ʒnəm], \spɪɹˈɪləm tˈaɪɹəʊdʒnəm], \s_p_ɪ_ɹ_ˈɪ_l_ə_m t_ˈaɪ_ɹ_əʊ_dʒ_n_ə_m]\
Definitions of SPIRILLUM TYROGENUM
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By Willam Alexander Newman Dorland
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.