SPIRILLUM OF GAMALEIA

\spɪɹˈɪləm ɒv ɡamˈe͡ɪli͡ə], \spɪɹˈɪləm ɒv ɡamˈe‍ɪli‍ə], \s_p_ɪ_ɹ_ˈɪ_l_ə_m ɒ_v ɡ_a_m_ˈeɪ_l_iə]\

Definitions of SPIRILLUM OF GAMALEIA

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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