PACHYDERMOPERIOSTOSES
\pˌat͡ʃa͡ɪdəmə͡ʊpˈi͡əɹɪˌɒstə͡ʊzɪz], \pˌatʃaɪdəməʊpˈiəɹɪˌɒstəʊzɪz], \p_ˌa_tʃ_aɪ_d_ə_m_əʊ_p_ˈiə_ɹ_ɪ__ˌɒ_s_t_əʊ_z_ɪ_z]\
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A conditioned chiefly characterized by thickening of the skin of the head and distal extremities, deep folds and furrows of the skin of the forehead, cheeks, and scalp, seborrhea, hyperhidrosis, periostosis of the long bones, digital clubbing, and spadelike enlargement of the hands and feet. It is more prevalent in the male, and is usually first evident during adolescence. It is believed to be inherited as an autosomal dominant trait. (From Dorland, 27th ed)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.