PACHYDERMATOSIS

\pˌat͡ʃa͡ɪdəmɐtˈə͡ʊsɪs], \pˌat‍ʃa‍ɪdəmɐtˈə‍ʊsɪs], \p_ˌa_tʃ_aɪ_d_ə_m_ɐ_t_ˈəʊ_s_ɪ_s]\

Definitions of PACHYDERMATOSIS

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1898 - American pocket medical dictionary
By Willam Alexander Newman Dorland

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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