PACHYDERMATOCELE
\pˈat͡ʃa͡ɪdəmˌatə͡ʊsə͡l], \pˈatʃaɪdəmˌatəʊsəl], \p_ˈa_tʃ_aɪ_d_ə_m_ˌa_t_əʊ_s_əl]\
Sort: Oldest first
-
A type of neurofibroma manifesting as a diffuse overgrowth of subcutaneous tissue, usually involving the face, scalp, neck, and chest but occasionally occurring in the abdomen or pelvis. The tumors tend to progress, and may extend along nerve roots to eventually involve the spinal roots and spinal cord. This process is almost always a manifestion of NEUROFIBROMATOSIS 1. (From Adams et al., Principles of Neurology, 6th ed, p1016; J Pediatr 1997 Nov;131 (5):678-82)
By DataStellar Co., Ltd
By William R. Warner
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.