SUPPOSITORIA PLUMBI COMPOSITA (BR.)

\sˌʌpəsɪtˈɔːɹi͡ə plˈʌmba͡ɪ kˌɒmpəsˈiːtə bˌiːˈɑː], \sˌʌpəsɪtˈɔːɹi‍ə plˈʌmba‍ɪ kˌɒmpəsˈiːtə bˌiːˈɑː], \s_ˌʌ_p_ə_s_ɪ_t_ˈɔː_ɹ_iə p_l_ˈʌ_m_b_aɪ k_ˌɒ_m_p_ə_s_ˈiː_t_ə__ b_ˌiː__ˈɑː]\

Definitions of SUPPOSITORIA PLUMBI COMPOSITA (BR.)

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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