STERIGMATOCYSTIN
\stˈɛɹɪɡmˌatəsˌɪstɪn], \stˈɛɹɪɡmˌatəsˌɪstɪn], \s_t_ˈɛ_ɹ_ɪ_ɡ_m_ˌa_t_ə_s_ˌɪ_s_t_ɪ_n]\
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A carcinogenic mycotoxin produced in high yields by strains of the common molds, Aspergillus versicolor, A. nidulans, and an unidentified species of Bipolaris. It causes necrosis of the liver and kidney and has an inhibitory effect on orotic acid incorporation into nuclear RNA.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.