PRELIMBIC

\pɹɪlˈɪmbɪk], \pɹɪlˈɪmbɪk], \p_ɹ_ɪ_l_ˈɪ_m_b_ɪ_k]\
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1898 - American pocket medical dictionary
By Willam Alexander Newman Dorland

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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