PEREZ'S SIGN
\pəɹˈɛzɪz sˈa͡ɪn], \pəɹˈɛzɪz sˈaɪn], \p_ə_ɹ_ˈɛ_z_ɪ_z s_ˈaɪ_n]\
Definitions of PEREZ'S SIGN
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.