PARADOXICAL DIAPHRAGM PHENOMENON

\pˌaɹədˈɒksɪkə͡l dˈa͡ɪəfɹˌam fɪnˈɒmɪnən], \pˌaɹədˈɒksɪkə‍l dˈa‍ɪəfɹˌam fɪnˈɒmɪnən], \p_ˌa_ɹ_ə_d_ˈɒ_k_s_ɪ_k_əl d_ˈaɪ_ə_f_ɹ_ˌa_m f_ɪ_n_ˈɒ_m_ɪ_n_ə_n]\

Definitions of PARADOXICAL DIAPHRAGM PHENOMENON

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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