PAGET DISEASE OF BONE
\pˈaɡɪt dɪzˈiːz ɒv bˈə͡ʊn], \pˈaɡɪt dɪzˈiːz ɒv bˈəʊn], \p_ˈa_ɡ_ɪ_t d_ɪ_z_ˈiː_z ɒ_v b_ˈəʊ_n]\
Sort: Oldest first
-
A disease marked by repeated episodes of increased bone resorption followed by excessive attempts at repair, resulting in weakened, deformed bones of increased mass. The resultant architecture of the bone assumes a mosaic pattern in which the fibers take on a haphazard pattern instead of the normal parallel symmetry.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.