PAGENSTECHER'S CIRCLE

\pˈe͡ɪd͡ʒnstɛt͡ʃəz sˈɜːkə͡l], \pˈe‍ɪd‍ʒnstɛt‍ʃəz sˈɜːkə‍l], \p_ˈeɪ_dʒ_n_s_t_ɛ_tʃ_ə_z s_ˈɜː_k_əl]\

Definitions of PAGENSTECHER'S CIRCLE

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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