NAPE OF THE NECK

\nˈe͡ɪp ɒvðə nˈɛk], \nˈe‍ɪp ɒvðə nˈɛk], \n_ˈeɪ_p ɒ_v_ð_ə n_ˈɛ_k]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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