GREENOUGH WHITE

\ɡɹˈiːnʌf wˈa͡ɪt], \ɡɹˈiːnʌf wˈa‍ɪt], \ɡ_ɹ_ˈiː_n_ʌ_f w_ˈaɪ_t]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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