GABRIELLO CHIABRERA

\ɡˌabɹɪˈɛlə͡ʊ t͡ʃˈa͡ɪəbɹəɹə], \ɡˌabɹɪˈɛlə‍ʊ t‍ʃˈa‍ɪəbɹəɹə], \ɡ_ˌa_b_ɹ_ɪ__ˈɛ_l_əʊ tʃ_ˈaɪ_ə_b_ɹ_ə_ɹ_ə]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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