FOLLITROPIN
\fˈɒlɪtɹˌɒpɪn], \fˈɒlɪtɹˌɒpɪn], \f_ˈɒ_l_ɪ_t_ɹ_ˌɒ_p_ɪ_n]\
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A gonadotropic hormone found in the anterior pituitary gland (PITUITARY GLAND, ANTERIOR) of mammals. It stimulates ovarian granulosa cells and testicular Sertoli cells, induces maturation of Graafian follicles in the ovary, and promotes the development of the germinal cells in the testis.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.