COILED SPRING
\kˈɔ͡ɪld spɹˈɪŋ], \kˈɔɪld spɹˈɪŋ], \k_ˈɔɪ_l_d s_p_ɹ_ˈɪ_ŋ]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.