UGO FOSCOLO

\jˈuːɡə͡ʊ fəskˈɒlə͡ʊ], \jˈuːɡə‍ʊ fəskˈɒlə‍ʊ], \j_ˈuː_ɡ_əʊ f_ə_s_k_ˈɒ_l_əʊ]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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