SYSTEMATIC LESION OF THE NERVOUS SYSTEM

\sˌɪstəmˈatɪk lˈiːʒən ɒvðə nˈɜːvəs sˈɪstəm], \sˌɪstəmˈatɪk lˈiːʒən ɒvðə nˈɜːvəs sˈɪstəm], \s_ˌɪ_s_t_ə_m_ˈa_t_ɪ_k l_ˈiː_ʒ_ə_n ɒ_v_ð_ə n_ˈɜː_v_ə_s s_ˈɪ_s_t_ə_m]\

Definitions of SYSTEMATIC LESION OF THE NERVOUS SYSTEM

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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