SPINDLE-SHAPED

\spˈɪndə͡lʃˈe͡ɪpt], \spˈɪndə‍lʃˈe‍ɪpt], \s_p_ˈɪ_n_d_əl_ʃ_ˈeɪ_p_t]\

Definitions of SPINDLE-SHAPED

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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