SHAK(E)SPE(A)RIAN

\ʃˈak ˈiː spˈiː ɐ ɹˈa͡ɪən], \ʃˈak ˈiː spˈiː ɐ ɹˈa‍ɪən], \ʃ_ˈa_k__ ˈiː__ s_p_ˈiː__ ɐ__ ɹ_ˈaɪ_ə_n]\
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1919 - The concise Oxford dictionary of current English
By Sir Augustus Henry

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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