QUINQUEVALENT

\kwˈɪnkwɪvˌe͡ɪlənt], \kwˈɪnkwɪvˌe‍ɪlənt], \k_w_ˈɪ_n_k_w_ɪ_v_ˌeɪ_l_ə_n_t]\

Definitions of QUINQUEVALENT

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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