PLUMBUM IODIDUM (N.F., BR.)

\plˈʌmbəm ˌa͡ɪədˈɪdəm ˌɛnˈɛf], \plˈʌmbəm ˌa‍ɪədˈɪdəm ˌɛnˈɛf], \p_l_ˈʌ_m_b_ə_m ˌaɪ_ə_d_ˈɪ_d_ə_m__ ˌɛ_n_ˈɛ_f]\

Definitions of PLUMBUM IODIDUM (N.F., BR.)

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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