PAVY'S DISEASE'S REAGENT

\pˈe͡ɪviz dɪzˈiːzɪz ɹɪˈe͡ɪd͡ʒənt], \pˈe‍ɪviz dɪzˈiːzɪz ɹɪˈe‍ɪd‍ʒənt], \p_ˈeɪ_v_i_z d_ɪ_z_ˈiː_z_ɪ_z ɹ_ɪ__ˈeɪ_dʒ_ə_n_t]\

Definitions of PAVY'S DISEASE'S REAGENT

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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