PARAKERATOSIS VARIEGATA

\pˌaɹəkəɹɐtˈə͡ʊsɪs vˌe͡əɹɪɡˈɑːtə], \pˌaɹəkəɹɐtˈə‍ʊsɪs vˌe‍əɹɪɡˈɑːtə], \p_ˌa_ɹ_ə_k_ə_ɹ_ɐ_t_ˈəʊ_s_ɪ_s v_ˌeə_ɹ_ɪ_ɡ_ˈɑː_t_ə]\
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2010 - Medical Dictionary Database
By DataStellar Co., Ltd
 
1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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