PARACHROMATOSIS
\pˌaɹəkɹˌə͡ʊmɐtˈə͡ʊsɪs], \pˌaɹəkɹˌəʊmɐtˈəʊsɪs], \p_ˌa_ɹ_ə_k_ɹ_ˌəʊ_m_ɐ_t_ˈəʊ_s_ɪ_s]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.