NECROSIS CEREALIS

\nɛkɹˈə͡ʊsɪs sˈi͡əɹɪə͡lˌiz], \nɛkɹˈə‍ʊsɪs sˈi‍əɹɪə‍lˌiz], \n_ɛ_k_ɹ_ˈəʊ_s_ɪ_s s_ˈiə_ɹ_ɪ__əl_ˌi_z]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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