MULTICYSTIC ENCEPHALOMALACIAS
\mˌʌltɪsˈɪstɪk ɛnsˌɛfɐlˌɒmɐlˈe͡ɪʃəz], \mˌʌltɪsˈɪstɪk ɛnsˌɛfɐlˌɒmɐlˈeɪʃəz], \m_ˌʌ_l_t_ɪ_s_ˈɪ_s_t_ɪ_k ɛ_n_s_ˌɛ_f_ɐ_l_ˌɒ_m_ɐ_l_ˈeɪ_ʃ_ə_z]\
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Softening or loss of brain tissue following CEREBRAL INFARCTION; cerebral ischemia (see BRAIN ISCHEMIA), infection, CRANIOCEREBRAL TRAUMA, or other injury. The term is often used during gross pathologic inspection to describe blurred cortical margins and decreased consistency of brain tissue following infarction. Multicystic encephalomalacia refers to the formation of multiple cystic cavities of various sizes in the cerebral cortex of neonates and infants following injury, most notably perinatal hypoxia-ischemic events. (From Davis et al., Textbook of Neuropathology, 2nd ed, p665; J Neuropathol Exp Neurol, 1995 Mar;54 (2):268-75)
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Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.