MODIFICATION METHYLASES (ADENINE SPECIFIC)

\mˌɒdɪfɪkˈe͡ɪʃən mˈiːθɪlˌe͡ɪsɪz ˈadənˌiːn spəsˈɪfɪk], \mˌɒdɪfɪkˈe‍ɪʃən mˈiːθɪlˌe‍ɪsɪz ˈadənˌiːn spəsˈɪfɪk], \m_ˌɒ_d_ɪ_f_ɪ_k_ˈeɪ_ʃ_ə_n m_ˈiː_θ_ɪ_l_ˌeɪ_s_ɪ_z__ ˈa_d_ə_n_ˌiː_n s_p_ə_s_ˈɪ_f_ɪ_k]\

Definitions of MODIFICATION METHYLASES (ADENINE SPECIFIC)

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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