MADGE-HOWLET

\mˈad͡ʒhˈa͡ʊlət], \mˈad‍ʒhˈa‍ʊlət], \m_ˈa_dʒ_h_ˈaʊ_l_ə_t]\

Definitions of MADGE-HOWLET

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1895 - Glossary of terms and phrases
By Henry Percy Smith

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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