JUSTICIA ECBOLIUM

\d͡ʒˈʌstɪʃəɹ ɛkbˈə͡ʊli͡əm], \d‍ʒˈʌstɪʃəɹ ɛkbˈə‍ʊli‍əm], \dʒ_ˈʌ_s_t_ɪ_ʃ_ə_ɹ ɛ_k_b_ˈəʊ_l_iə_m]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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