JARISCH-HERXHEIMER REACTION

\d͡ʒˈɑːɹɪʃhˈɜːksha͡ɪmə ɹɪˈakʃən], \d‍ʒˈɑːɹɪʃhˈɜːksha‍ɪmə ɹɪˈakʃən], \dʒ_ˈɑː_ɹ_ɪ_ʃ_h_ˈɜː_k_s_h_aɪ_m_ə ɹ_ɪ__ˈa_k_ʃ_ə_n]\

Definitions of JARISCH-HERXHEIMER REACTION

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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