INBRED CFTR MICE
\ˈɪnbɹɛd sˌiːˌɛftˌiːˈɑː mˈa͡ɪs], \ˈɪnbɹɛd sˌiːˌɛftˌiːˈɑː mˈaɪs], \ˈɪ_n_b_ɹ_ɛ_d s_ˌiː__ˌɛ_f_t_ˌiː__ˈɑː m_ˈaɪ_s]\
Sort: Oldest first
-
A strain of mice widely studied as a model for cystic fibrosis. These mice are generated from embryonic stem cells in which the CFTR (cystic fibrosis transmembrane conductance regulator) gene is inactivated by gene targeting. As a result, all mice have one copy of this altered gene in all their tissues. Mice homozygous for the disrupted gene exhibit many features common to young cystic fibrosis patients, including failure to thrive, meconium ileus, and alteration of mucous and serous glands.
By DataStellar Co., Ltd
Word of the day
dust storm
- a windstorm that lifts up clouds of dust or sand a windstorm that lifts up clouds dust or sand; "it was the kind of duster not experienced in years"