HYPERCATAPINOSIS

\hˌa͡ɪpəkˌatɐpɪnˈə͡ʊsɪs], \hˌa‍ɪpəkˌatɐpɪnˈə‍ʊsɪs], \h_ˌaɪ_p_ə_k_ˌa_t_ɐ_p_ɪ_n_ˈəʊ_s_ɪ_s]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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