HYDROMININGITIS

\hˌa͡ɪdɹəmˌa͡ɪnɪnd͡ʒˈa͡ɪtɪs], \hˌa‍ɪdɹəmˌa‍ɪnɪnd‍ʒˈa‍ɪtɪs], \h_ˌaɪ_d_ɹ_ə_m_ˌaɪ_n_ɪ_n_dʒ_ˈaɪ_t_ɪ_s]\
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1900 - A dictionary of medicine and the allied sciences
By Alexander Duane

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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