HOLDEN, EDWARD S.
\hˈə͡ʊldən], \hˈəʊldən], \h_ˈəʊ_l_d_ə_n]\
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Born in 1846, was connected with the U.S. Naval Observatory from 1873 to 1886, when he became director of the Lick Observatory. He is the author of a life of Sir William Herschel and "Monograph of the Central Parts of the Nebula of Orion," an exhaustive treatise.
By John Franklin Jameson
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.