HOFFMANN-WERDNIG SYNDROME
\hˈɒfmanwˈɜːdnɪɡ sˈɪndɹə͡ʊm], \hˈɒfmanwˈɜːdnɪɡ sˈɪndɹəʊm], \h_ˈɒ_f_m_a_n_w_ˈɜː_d_n_ɪ_ɡ s_ˈɪ_n_d_ɹ_əʊ_m]\
Definitions of HOFFMANN-WERDNIG SYNDROME
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.