DESOXYPHENOBARBITAL
\dɪsˈɒksɪfənˌɒbɑːbˌɪtə͡l], \dɪsˈɒksɪfənˌɒbɑːbˌɪtəl], \d_ɪ_s_ˈɒ_k_s_ɪ_f_ə_n_ˌɒ_b_ɑː_b_ˌɪ_t_əl]\
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An antiepileptic agent related to the barbiturates; it is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite. Adverse effects are reported to be more frequent than with PHENOBARBITAL. (From Martindale, The Extra Pharmacopoeia, 30th ed, p309)
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.