CAST ASIDE
\kˈast ɐsˈa͡ɪd], \kˈast ɐsˈaɪd], \k_ˈa_s_t ɐ_s_ˈaɪ_d]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.