BRL4910A

\bˌiːˌɑːɹˈɛl fˈɔː θˈa͡ʊzənd nˈa͡ɪnhˈʌndɹədən tˈɛn ˈe͡ɪ], \bˌiːˌɑːɹˈɛl fˈɔː θˈa‍ʊzənd nˈa‍ɪnhˈʌndɹədən tˈɛn ˈe‍ɪ], \b_ˌiː__ˌɑː_ɹ_ˈɛ_l f_ˈɔː θ_ˈaʊ_z_ə_n_d n_ˈaɪ_n_h_ˈʌ_n_d_ɹ_ə_d_ə_n t_ˈɛ_n ˈeɪ]\

Definitions of BRL4910A

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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