BRIDLE IRON

\bɹˈa͡ɪdə͡l ˈa͡ɪ͡ən], \bɹˈa‍ɪdə‍l ˈa‍ɪ‍ən], \b_ɹ_ˈaɪ_d_əl ˈaɪə_n]\

Definitions of BRIDLE IRON

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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