BLANCNON ORIBASII

\blˈanknɒn ˈɒɹɪbˌe͡ɪsɪˌa͡ɪ], \blˈanknɒn ˈɒɹɪbˌe‍ɪsɪˌa‍ɪ], \b_l_ˈa_n_k_n_ɒ_n ˈɒ_ɹ_ɪ_b_ˌeɪ_s_ɪ__ˌaɪ]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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