BLADDER CAMPION

\blˈadə kˈampi͡ən], \blˈadə kˈampi‍ən], \b_l_ˈa_d_ə k_ˈa_m_p_iə_n]\

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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