BENITO PEREZ GALDOS

\bɪnˈiːtə͡ʊ pəɹˈɛz ɡˈaldə͡ʊz], \bɪnˈiːtə‍ʊ pəɹˈɛz ɡˈaldə‍ʊz], \b_ɪ_n_ˈiː_t_əʊ p_ə_ɹ_ˈɛ_z ɡ_ˈa_l_d_əʊ_z]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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