AUTREFOIS ATTAINT

\ˈɔːtɹɪfwˌɑːɹ ɐtˈe͡ɪnt], \ˈɔːtɹɪfwˌɑːɹ ɐtˈe‍ɪnt], \ˈɔː_t_ɹ_ɪ_f_w_ˌɑː_ɹ ɐ_t_ˈeɪ_n_t]\
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1910 - Black's Law Dictionary (2nd edition)
By Henry Campbell Black

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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