ALVINE FLUX
\ˈalva͡ɪn flˈʌks], \ˈalvaɪn flˈʌks], \ˈa_l_v_aɪ_n f_l_ˈʌ_k_s]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.