ALOYS SENEFELDER
\ɐlˈɔ͡ɪz sˈɛnɪfˌɛldə], \ɐlˈɔɪz sˈɛnɪfˌɛldə], \ɐ_l_ˈɔɪ_z s_ˈɛ_n_ɪ_f_ˌɛ_l_d_ə]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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